BDBM222109 (E)-4-(3-Nitrophenyl)-2-(2-(pyren-1-ylmethylene)hydrazinyl)thiazole (8)

SMILES [O-][N+](=O)c1cccc(c1)-c1csc(N\N=C\c2ccc3ccc4cccc5ccc2c3c45)n1

InChI Key InChIKey=RXGQJBAODRDPES-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222109   

TargetBeta-glucuronidase(Bovine)
University of Karachi

LigandPNGBDBM222109((E)-4-(3-Nitrophenyl)-2-(2-(pyren-1-ylmethylene)hy...)
Affinity DataIC50: 3.10E+3nMAssay Description:β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM222109((E)-4-(3-Nitrophenyl)-2-(2-(pyren-1-ylmethylene)hy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM222109((E)-4-(3-Nitrophenyl)-2-(2-(pyren-1-ylmethylene)hy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed