BDBM222100 1-(4-Aminosulfonylphenyl)-5-(4-fluorophenyl)-3-(4-methanesulfonylaminophenyl)-4,5-dihydro-1H-pyrazole (6d)

SMILES CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccc(F)cc1)c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=LICMNNDJMFGUGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222100   

TargetProstaglandin G/H synthase 1(Sheep)
Fayoum University

LigandPNGBDBM222100(1-(4-Aminosulfonylphenyl)-5-(4-fluorophenyl)-3-(4-...)
Affinity DataIC50: 1.87E+4nMAssay Description:The ability of the tested compounds to inhibit both isozymes, COX-1 and COX-2 was measured using colorimetric COX (ovine) Inhibitor Screening Assay K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Fayoum University

LigandPNGBDBM222100(1-(4-Aminosulfonylphenyl)-5-(4-fluorophenyl)-3-(4-...)
Affinity DataIC50: 3.90E+3nMAssay Description:The ability of the tested compounds to inhibit both isozymes, COX-1 and COX-2 was measured using colorimetric COX (ovine) Inhibitor Screening Assay K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2017
Entry Details Article
PubMed