BDBM22119 aza-peptide Michael acceptor, 5c::benzyl N-[(1S)-1-{[(2S)-1-[(2E)-N-(carbamoylmethyl)-4-oxo-4-(piperidin-1-yl)but-2-enehydrazido]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamate

SMILES C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)NN(CC(N)=O)C(=O)C=CC(=O)N1CCCCC1

InChI Key InChIKey=JAWCSPSOVNQLPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22119   

TargetLegumain(Blood fluke)
Georgia Institute of Technology

LigandPNGBDBM22119(benzyl N-[(1S)-1-{[(2S)-1-[(2E)-N-(carbamoylmethyl...)
Affinity DataIC50: 1.00E+3nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2008
Entry Details Article
PubMed
TargetClan CD, family C13, asparaginyl endopeptidase-like cysteine peptidase(Trichomonas vaginalis G3)
Georgia Institute of Technology

LigandPNGBDBM22119(benzyl N-[(1S)-1-{[(2S)-1-[(2E)-N-(carbamoylmethyl...)
Affinity DataIC50: 500nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2008
Entry Details Article
PubMed