BDBM220320 US9290476, 71B::US9290476, 71C

SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Cc3ccc(cc3)-n3cccn3)c(C#N)c2c1

InChI Key InChIKey=PLTOQAMSCRJXOS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220320   

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220320(US9290476, 71C | US9290476, 71B)
Affinity DataKd:  1.60nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220320(US9290476, 71C | US9290476, 71B)
Affinity DataKd:  130nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent