BDBM220142 US9278925, 1-3

SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)OC

InChI Key InChIKey=UXFQAQYZDQWZHD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 220142   

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220142(US9278925, 1-3)
Affinity DataIC50: 165nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220142(US9278925, 1-3)
Affinity DataIC50: 146nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220142(US9278925, 1-3)
Affinity DataIC50: 8.08E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220142(US9278925, 1-3)
Affinity DataIC50: 6.55E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent