BDBM220133 US9278925, V.2-a::US9278925, V.4-a

SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1

InChI Key InChIKey=FTSZDPCKVAXHPT-UHFFFAOYSA-N

Data  40 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 220133   

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 9.56E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 9.20E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 4.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 5.80E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 8.63E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 7.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 8.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 3.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 2.14E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 9.56E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 9.20E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 4.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 5.80E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 8.63E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 7.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 8.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 3.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 2.14E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [27-2458](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 83nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 249nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 154nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 87nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 75nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 83nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 249nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 154nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 87nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1 [39-2346](Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.4-a | US9278925, V.2-a)
Affinity DataIC50: 75nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent