BDBM220123 US9271961, BMT 5-119

SMILES OC(=O)c1ccccc1Nc1cc(ccc1N(=O)=O)C(F)(F)F

InChI Key InChIKey=FZAWUOZTOMHTKK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 220123   

TargetAldo-keto reductase family 1 member C4(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 30nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 4.35E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 4.23E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member B1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 5.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetProstaglandin G/H synthase 1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetProstaglandin G/H synthase 2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent