BDBM21932 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[({4-[3-(dimethylamino)propyl]-1H-imidazol-5-yl}methyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 43

SMILES CN(C)CCCc1nc[nH]c1CNc1cc(Cl)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1

InChI Key InChIKey=SZCUOFTYYJGMNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21932   

LigandPNGBDBM21932(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[({4...)
Affinity DataIC50: 130nMAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed