BDBM21921 8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(2,3-dihydroxypropyl)amino]quinoline-3-carbonitrile::Cyanoquinoline, 34

SMILES OCC(O)CNc1cc(Br)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1

InChI Key InChIKey=GBWAKUBDAHZEBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21921   

LigandPNGBDBM21921(8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(2,3...)
Affinity DataIC50: 590nMpH: 7.2 T: 2°CAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2008
Entry Details Article
PubMed