BDBM21913 8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-{[(1-phenyl-1H-pyrazol-5-yl)methyl]amino}quinoline-3-carbonitrile::Cyanoquinoline, 26

SMILES Fc1ccc(Nc2c(cnc3c(Br)cc(NCc4ccnn4-c4ccccc4)cc23)C#N)cc1Cl

InChI Key InChIKey=UWKYOOXSHMIYSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21913   

LigandPNGBDBM21913(8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-{[(1-...)
Affinity DataIC50: 250nMpH: 7.2 T: 2°CAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2008
Entry Details Article
PubMed