BDBM218243 US9260435, 1

SMILES NC1(CCC1)c1ccc(cc1)-c1nc2c(O)nccn2c1-c1ccccc1

InChI Key InChIKey=YRJOCSPCUOAQGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218243   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM218243(US9260435, 1)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:His-tagged human recombinant kinase full-length Akt1 expressed in insect cells was purchased form Invitrogen (part number PV 3599). As substrate for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM218243(US9260435, 1)
Affinity DataIC50: 970nMpH: 7.5 T: 2°CAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased from Invitrogen (part number PV 39...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent