BDBM218202 US9249087, 43

SMILES ONC(=O)c1ccc(Cn2cccn2)cc1

InChI Key InChIKey=DUGDSZFLAKVUEC-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 218202   

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50: 1.47E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50: 10.9nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataEC50:  932nMAssay Description:Inhibition of HDAC6 in mouse N2A cells assessed as increase in alpha tubulin acetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of HDAC1 in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50: 46nMAssay Description:Inhibition of HDAC6 in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed