BDBM217959 US10729684, Example 10::US9212182, 643

SMILES COc1cc(C#CC2CCCC2)c(F)cc1-n1c2ccc(cc2ccc1=O)S(=O)(=O)Nc1ccon1

InChI Key InChIKey=ZUMUVHCYKSEVIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 217959   

LigandPNGBDBM217959(US9212182, 643 | US10729684, Example 10)
Affinity DataIC50: 22nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
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LigandPNGBDBM217959(US9212182, 643 | US10729684, Example 10)
Affinity DataIC50: 4.53nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM217959(US9212182, 643 | US10729684, Example 10)
Affinity DataIC50: 17.3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent