BDBM21775 2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 17v

SMILES CC(=O)Nc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-n1ccnn1

InChI Key InChIKey=YYSCULLHLGWVSS-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21775   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21775(2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl...)
Affinity DataEC50:  9.20E+3nMpH: 7.4 T: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21775(2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl...)
Affinity DataEC50:  367nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21775(2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl...)
Affinity DataEC50:  5.60E+3nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21775(2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl...)
Affinity DataEC50:  2.72E+6nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21775(2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl...)
Affinity DataEC50:  1.09E+5nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetPeroxisome proliferator-activated receptor gamma(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21775(2-[(1S)-5-{3-[2-acetamido-4-(1H-1,2,3-triazol-1-yl...)
Affinity DataEC50:  1.82E+5nMAssay Description:Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article