BDBM217332 US9303018, 5

SMILES O[C@H]1CCN(C2CCN(Cc3cnc4cc(Oc5ccc(cn5)-c5ccn[nH]5)ccc4c3)CC2)C1=O

InChI Key InChIKey=VRNHRFCAVNZHII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 217332   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM217332(US9303018, 5)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2017
Entry Details
US Patent