BDBM21723 3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4-phenylphenyl)-1,2-oxazol-4-yl]methoxy}benzene)amido]benzoic acid::Isoxazole derivative, 15h

SMILES OC(=O)c1cccc(NC(=O)c2ccc(OCc3c(noc3-c3ccc(cc3)-c3ccccc3)-c3c(Cl)cccc3Cl)cc2Cl)c1

InChI Key InChIKey=MTKXOBLNUXRWGQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21723   

TargetBile acid receptor(Human)
University of Tokyo

LigandPNGBDBM21723(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4-pheny...)
Affinity DataEC50:  3.70E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Tokyo

LigandPNGBDBM21723(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4-pheny...)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed