BDBM21721 3-[(4-{[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-2-chlorobenzene)amido]benzoic acid::Isoxazole derivative, 15f

SMILES CC(C)(C)c1onc(c1COc1ccc(C(=O)Nc2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=ZQFCMJUELRQQFZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21721   

TargetBile acid receptor(Human)
University of Tokyo

LigandPNGBDBM21721(3-[(4-{[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-ox...)
Affinity DataEC50:  1.30E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed