BDBM21719 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(naphthalen-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid::Isoxazole derivative, 10f

SMILES OC(=O)c1cccc(\C=C\c2ccc(OCc3c(noc3-c3ccc4ccccc4c3)-c3c(Cl)cccc3Cl)cc2Cl)c1

InChI Key InChIKey=UCUWYYXYNMNGTN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21719   

TargetBile acid receptor(Human)
University of Tokyo

LigandPNGBDBM21719(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(n...)
Affinity DataEC50:  2.22E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed