BDBM21713 3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}benzene)(methyl)amido]benzoic acid::Isoxazole derivative, 15b

SMILES CC(C)c1onc(c1COc1ccc(C(=O)N(C)c2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=OQAKDJLSFYPIPF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21713   

TargetBile acid receptor(Human)
University of Tokyo

LigandPNGBDBM21713(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  3.10E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Tokyo

LigandPNGBDBM21713(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed