BDBM21632 (2S)-3-(1H-indol-3-yl)-2-[2-(3-phenylphenyl)-3-sulfanylpropanamido]propanoic acid::Mercaptoacyl amino acid compound, (rac)-6::racemic mixture

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(CS)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=FCBRDLHNEHOMLV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21632   

TargetNeprilysin(Rabbit)
Cnrs

LigandPNGBDBM21632((2S)-3-(1H-indol-3-yl)-2-[2-(3-phenylphenyl)-3-sul...)
Affinity DataKi:  35nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
LigandPNGBDBM21632((2S)-3-(1H-indol-3-yl)-2-[2-(3-phenylphenyl)-3-sul...)
Affinity DataKi:  150nMAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
LigandPNGBDBM21632((2S)-3-(1H-indol-3-yl)-2-[2-(3-phenylphenyl)-3-sul...)
Affinity DataKi:  900nMAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed