BDBM215526 US9296745, 82

SMILES O=C([C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)C1(CC1)c1ccccn1)N1CCCC1

InChI Key InChIKey=ZOLXCZYWGVXESO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215526   

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215526(US9296745, 82)
Affinity DataIC50: 165nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215526(US9296745, 82)
Affinity DataIC50: 15.8nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
Go to US Patent