BDBM214798 Dynorphin A (1-17)::YGGFLRRIRPKLK

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=OVVIBUHLQIYUEU-UHFFFAOYSA-N

Data  32 KI  3 IC50  27 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 62 hits for monomerid = 214798   

TargetKappa-type opioid receptor [I294A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  72nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Q115A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  65nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y119A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  55nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y119F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  3.80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [D138N](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  1.90E+3nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y139A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  120nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y139F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  22nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [M142A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  110nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [K200A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  2nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [K212A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [M226A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  1.40nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [K227A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  12nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [H291A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  260nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [H291F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  81nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [I135A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  21nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [E297A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  44nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y312A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  47nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y312F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  5.80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y313A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  30nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y313F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  5.90nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [I316A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  100nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y320F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  76nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y320A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  100nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mu opioid receptor in guinea pig ileum/longitudinal muscle with myenteric plexus assessed as inhibition of electrically-stimulated musc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataIC50: 6.30nMAssay Description:Inhibition of delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataIC50: 0.148nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  159nMAssay Description:Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin 2 recruitment using furimazine as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  6.70nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  4.80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y66A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  10nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in mouse HN9.10 cell membranes incubated for 2 hrs by liquid scintillation counting based radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor [K227A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  2.20nM ΔG°:  -11.8kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  4nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor [K200A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  4.80nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [K212A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  5.40nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [I135A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  6.20nM ΔG°:  -11.2kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y320A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  6.60nM ΔG°:  -11.2kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [M226A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  7.10nM ΔG°:  -11.1kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  8nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in mouse NG108-15 cell membranes incubated for 2 hrs by liquid scintillation counting base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  8nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]deltorphin-II from human DOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting based radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y313F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  10nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y312A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  11nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [M142A](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  16nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [H291F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  17nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y320F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  18nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y312F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  19nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor [Y119F](Human)
University of North Carolina

LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  20nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed
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