BDBM214700 US9296728, 23

SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(CC=C)CC=C

InChI Key InChIKey=CNKJPGDJYDBWCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 214700   

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM214700(US9296728, 23)
Affinity DataIC50: 250nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2017
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM214700(US9296728, 23)
Affinity DataIC50: 170nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed