BDBM214648 US9284319, R6::US9730929, Example R6::US9783543, R6

SMILES C(Cc1ccccn1)Nc1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key InChIKey=ZSRHNAGHFRMYJX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 214648   

LigandPNGBDBM214648(US9284319, R6 | US9730929, Example R6 | US9783543,...)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

LigandPNGBDBM214648(US9284319, R6 | US9730929, Example R6 | US9783543,...)
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214648(US9284319, R6 | US9730929, Example R6 | US9783543,...)
Affinity DataIC50: 17nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214648(US9284319, R6 | US9730929, Example R6 | US9783543,...)
Affinity DataIC50: 250nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214648(US9284319, R6 | US9730929, Example R6 | US9783543,...)
Affinity DataIC50: 250nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent