BDBM21384 6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 22

SMILES CN(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1

InChI Key InChIKey=AYPZPRUFAPTKJJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21384   

Target5-hydroxytryptamine receptor 7(Rat)
Universita Degli Studi Di Bari

LigandPNGBDBM21384(6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1...)
Affinity DataKi:  0.900nM ΔG°:  -12.8kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Universita Degli Studi Di Bari

LigandPNGBDBM21384(6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1...)
Affinity DataKi:  32nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universita Degli Studi Di Bari

LigandPNGBDBM21384(6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1...)
Affinity DataKi:  112nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandPNGBDBM21384(6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1...)
Affinity DataKi:  559nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed