BDBM213737 US9284284, 28

SMILES C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(Nc2ncnc3cc(cnc23)C(F)(F)F)ccc1F

InChI Key InChIKey=NTKVVULXBBNHFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213737   

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM213737(US9284284, 28)
Affinity DataIC50: 68nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 1 nM concentrations is incubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM213737(US9284284, 28)
Affinity DataIC50: 200nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 1 nM concentrations is incubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent