BDBM21320 1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indol-4-amine::Morpholino-ethyl analogue, 41

SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3cccc(N)c23)C1(C)C

InChI Key InChIKey=XCBYGYHHTWZKKL-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21320   

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM21320(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Affinity DataKi:  32nM EC50:  215nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM21320(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Abbott Laboratories

LigandPNGBDBM21320(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Affinity DataKi: >3.50E+3nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Abbott Laboratories

LigandPNGBDBM21320(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed