BDBM213178 US9278963, 026

SMILES CC(C)[C@H](C(=O)N1CCC(CC1)(Nc1ncc(cn1)C(=O)NO)c1ccccc1)c1ccccc1

InChI Key InChIKey=DOSFADKGXFNINV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 213178   

TargetHistone deacetylase 1(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM213178(US9278963, 026)
Affinity DataIC50: 206nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
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TargetHistone deacetylase 2(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM213178(US9278963, 026)
Affinity DataIC50: 173nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM213178(US9278963, 026)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM213178(US9278963, 026)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
Go to US Patent