BDBM213101 US9278960, 8-1::US9636337, 8-1

SMILES NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(cc2n1)[C@@H](O)Cc1ccc(Cl)nc1

InChI Key InChIKey=CWRYRTIWJWUWEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 213101   

LigandPNGBDBM213101(US9278960, 8-1 | US9636337, 8-1)
Affinity DataIC50: 10nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213101(US9278960, 8-1 | US9636337, 8-1)
Affinity DataIC50: 10nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213101(US9278960, 8-1 | US9636337, 8-1)
Affinity DataIC50: 15nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent