BDBM212636 BDBM212752::US9278954, 1.27

SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2nc(ncc2F)N(C)C)cc1

InChI Key InChIKey=DRWWBYIFRZZNGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212636   

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212636(US9278954, 1.27 | BDBM212752)
Affinity DataIC50: 345nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212636(US9278954, 1.27 | BDBM212752)
Affinity DataIC50: 126nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent