BDBM212623 US9278954, 1.14::US9278954, 1.22

SMILES CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(F)F)c2F)cc1

InChI Key InChIKey=BKLDPPGZLFZGFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212623   

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212623(US9278954, 1.22 | US9278954, 1.14)
Affinity DataIC50: 244nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212623(US9278954, 1.22 | US9278954, 1.14)
Affinity DataIC50: 311nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent