BDBM21261 1-(3,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide::Pyrazole-3-carboxamide analogue, 28

SMILES Cc1c(nn(c1-n1cccc1)-c1ccc(Cl)c(Cl)c1)C(=O)NN1CCCCC1

InChI Key InChIKey=OPYOJVJATARELS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21261   

TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

LigandPNGBDBM21261(1-(3,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...)
Affinity DataKi:  20nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

LigandPNGBDBM21261(1-(3,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM21261(1-(3,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM21261(1-(3,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...)
Affinity DataKi:  30nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed