BDBM212512 US10155731, Example 70::US9278944, 70

SMILES COCCCn1nc(C)c2c(F)cc(cc12)[C@@H](C)N(C1CC1)C(=O)[C@H]1CNCCO1

InChI Key InChIKey=OCXRBMZFTAFVRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212512   

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212512(US9278944, 70 | US10155731, Example 70)
Affinity DataIC50: 0.600nMAssay Description:A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212512(US9278944, 70 | US10155731, Example 70)
Affinity DataIC50: 0.600nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent