BDBM212488 US10155731, Example 42::US9278944, 42

SMILES COC(=O)NCCCn1cc(C(C)N(C2CC2)C(=O)[C@H]2CNCCO2)c2cccnc12

InChI Key InChIKey=LKUGETCFXYSPQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212488   

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212488(US9278944, 42 | US10155731, Example 42)
Affinity DataIC50: 1.5nMAssay Description:A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212488(US9278944, 42 | US10155731, Example 42)
Affinity DataIC50: 1.5nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent