BDBM21247 4-cyano-N-[(3,4-dichlorophenyl)methyl]-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide::Pyrazole-3-carboxamide analogue, 14

SMILES Clc1ccc(CNC(=O)c2nn(c(c2C#N)-n2cccc2)-c2ccccc2)cc1Cl

InChI Key InChIKey=QILUOVIHJROTFV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21247   

TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

LigandPNGBDBM21247(4-cyano-N-[(3,4-dichlorophenyl)methyl]-1-phenyl-5-...)
Affinity DataKi:  280nM ΔG°:  -9.08kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

LigandPNGBDBM21247(4-cyano-N-[(3,4-dichlorophenyl)methyl]-1-phenyl-5-...)
Affinity DataKi:  3.94E+3nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed