BDBM212116 US9290485, 148

SMILES Cc1cc(C)n(Cc2ccc(Cn3cc(nn3)C(=O)NCc3c(C)cc(N)nc3C)cc2)n1

InChI Key InChIKey=FGZWHKYFVTWNMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 212116   

TargetPlasma kallikrein(Human)
Novartis

US Patent
LigandPNGBDBM212116(US9290485, 148)
Affinity DataIC50: 0.0300nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in assay buffer , comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For the det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM212116(US9290485, 148)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human fXIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetKallikrein-1(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM212116(US9290485, 148)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human KLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed