BDBM21182 CHEMBL270761::N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]-2-(4-methylpiperazin-1-yl)acetamide::Pyrimidine analogue, 34
SMILES CN1CCN(CC(=O)Nc2cc(nc(n2)-n2nc(C)cc2C)-c2nccs2)CC1
InChI Key InChIKey=QHUIIOCQAIOLJY-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 21182
Affinity DataKi: 27nM ΔG°: -10.2kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nM ΔG°: -7.79kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of [3H]DPCPX form human adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair