BDBM211307 US9247759, 10-55

SMILES Cc1noc(C)c1CN1CC(=O)N(C1=O)c1cnn(Cc2c(C)noc2C)c1

InChI Key InChIKey=OUQYWKVKGLQJDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211307   

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM211307(US9247759, 10-55)
Affinity DataIC50: 40nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM211307(US9247759, 10-55)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed