BDBM211296 US10093650, Example 11::US10329273, Example 11::US11479538, Example 11

SMILES Fc1cc(CCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F

InChI Key InChIKey=LQEYPJWBBIAXMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 211296   

LigandPNGBDBM211296(US10093650, Example 11 | US10329273, Example 11 | ...)
Affinity DataIC50: 9nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM211296(US10093650, Example 11 | US10329273, Example 11 | ...)
Affinity DataIC50: 9nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM211296(US10093650, Example 11 | US10329273, Example 11 | ...)
Affinity DataIC50: 9nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent