BDBM21104 3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-[3-(trifluoromethyl)phenyl]urea::Aminobenzoisoxazole, 50

SMILES COc1ccc(-c2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)cc2)c2c(N)noc12

InChI Key InChIKey=PATGADWTCHRVOQ-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 21104   

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 56nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 19nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 16nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 30nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 130nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 270nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM21104(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50: 11nM EC50:  31nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed