BDBM210974 US9247759, 4-8

SMILES Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3OCOc3c2)cn1

InChI Key InChIKey=PDPLBSHKAXBPBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210974   

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM210974(US9247759, 4-8)
Affinity DataIC50: 200nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM210974(US9247759, 4-8)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed