BDBM21093 3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-fluorophenyl)urea::Aminobenzoisoxazole, 36

SMILES Nc1noc2cccc(-c3ccc(NC(=O)Nc4ccc(F)cc4)cc3)c12

InChI Key InChIKey=SXSIVJXOXSHKPK-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21093   

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM21093(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-flu...)
Affinity DataIC50: 7nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM21093(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-flu...)
Affinity DataIC50: 4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM21093(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-flu...)
Affinity DataIC50: 134nM EC50:  23nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed