BDBM210893 US9273043, A122(e)

SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccccc2s1)c1ncc(cc1F)[C@@H](O)CO

InChI Key InChIKey=UWYWVDMYBPLDHY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 210893   

LigandPNGBDBM210893(US9273043, A122(e))
Affinity DataIC50: 80.6nMpH: 7.4Assay Description:One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent

LigandPNGBDBM210893(US9273043, A122(e))
Affinity DataIC50: 5.80nMpH: 7.2 T: 2°CAssay Description:pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent

LigandPNGBDBM210893(US9273043, A122(e))
Affinity DataIC50: 96nMT: 2°CAssay Description:Briefly, hTRPV1/CHO cells were cultured in growth media in a tissue culture dish at 37° C. in a CO2 incubator. On the day of the assay, culture m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent