BDBM21084 3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-methylphenyl)urea::Aminobenzoisoxazole, 27

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3onc(N)c23)c1

InChI Key InChIKey=MIDUFBKQPOWGMC-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21084   

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM21084(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-met...)
Affinity DataIC50: 12nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM21084(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-met...)
Affinity DataIC50: 14nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM21084(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-met...)
Affinity DataIC50: 7nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed