BDBM210748 US9290454, 2.1

SMILES C[C@@H](NC(=O)c1ccc2c(c1)cc(CC(O)=O)n(-c1ccc(F)cc1)c2=O)c1ccc(F)cc1

InChI Key InChIKey=ALNYGGOIUJUKCH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210748   

TargetProstaglandin D2 receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM210748(US9290454, 2.1)
Affinity DataKi:  4.92E+3nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM210748(US9290454, 2.1)
Affinity DataKi:  4.92E+3nM ΔG°:  -7.84kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding was performed using filtration or scintillation proximity assay (SPA) technology. SPA assays were done at room temperature in 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent