BDBM210747 US9290454, 1.2

SMILES C[C@@H](NC(=O)c1ccc2c(c1)cc(CCCCC(O)=O)n(Cc1ccc(F)cc1)c2=O)c1ccc(F)cc1

InChI Key InChIKey=HUEONONVVDTHFC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210747   

TargetProstaglandin D2 receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM210747(US9290454, 1.2)
Affinity DataKi:  49nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM210747(US9290454, 1.2)
Affinity DataKi:  49.0nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding was performed using filtration or scintillation proximity assay (SPA) technology. SPA assays were done at room temperature in 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent