BDBM209927 PKUMDL-WQ-2203

SMILES OC(=O)CSC1=C(SCC(O)=O)C(=O)C(SCC(O)=O)=C(SCC(O)=O)C1=O

InChI Key InChIKey=UHYAMQHNYHIPBZ-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 209927   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Peking University

LigandPNGBDBM209927(PKUMDL-WQ-2203)
Affinity DataKd:  7.22E+3nMpH: 7.4Assay Description:The binding affinities of compounds towards PHGDH were assayed using the SPR-based Biacore T200 instrument (GE Healthcare). PHGDH was immobilized on ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Peking University

LigandPNGBDBM209927(PKUMDL-WQ-2203)
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of human full-length PHGDH incubated for 10 mins by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Peking University

LigandPNGBDBM209927(PKUMDL-WQ-2203)
Affinity DataIC50: 2.81E+4nMpH: 7.1Assay Description:To evaluate the effects of compounds on PHGDH activity, compounds were first pre-incubated with enzyme samples in the assay buffer (25 mM HEPES, pH 7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed