BDBM209655 US9273029, A16

SMILES Nc1ncc(cc1C(=O)Nc1ccnnc1)-c1ccc(CN2CCOCC2)s1

InChI Key InChIKey=ISADMOXHYKRVEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 209655   

TargetSerine/threonine-protein kinase TBK1(Human)
Merck Patent

US Patent
LigandPNGBDBM209655(US9273029, A16)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well Flashplate assay assay (for e.g. Topcount measurement. 0.6 nM TANK binding kinase (TBK1), 800 nM biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

LigandPNGBDBM209655(US9273029, A16)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed either as 384-well Flashplate assay (for e.g. Topcount measurement). 1 nM IKKepsilon, 800 nM biotinylated IkappaBalpha(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Merck Patent

US Patent
LigandPNGBDBM209655(US9273029, A16)
Affinity DataIC50: 9.30E+3nMAssay Description:Assay Overview: MDA-MB-468 cells are detached with HyQ-Tase, counted, and seeded into a 384-well clear bottom TC-surface plate at density of 10,000 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent