BDBM209441 US9546153, ex. 133

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC12CCC(O)(CC1)C2

InChI Key InChIKey=HTLPWUOPXXCDSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209441   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209441(US9546153, ex. 133)
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
Go to US Patent