BDBM208526 US9266870, 42

SMILES Cc1ccc(c(c1)C(=O)N1CCCOC1Cc1cnn(c1)-c1ccc(F)cn1)-c1ncccn1

InChI Key InChIKey=XREXIMFORJAGEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208526   

TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208526(US9266870, 42)
Affinity DataIC50: 17.2nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208526(US9266870, 42)
Affinity DataIC50: 20.4nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent